Posts Tagged ‘Bio-Rad Laboratories’
Bio-Rad Laboratories, Inc. announced the release of its Bio-Plex Manager MP Software Upgrade, which runs on all Luminex-based MAGPIX readers. Users of Bio-Rad’s Bio-Plex® MAGPIX™ instruments have already benefited from the ease of use and improved instrument performance that Bio-Plex Manager MP software brings to multiplex experiments, and now, with Bio-Plex Manager MP Software Upgrade, these benefits are available on all Luminex-based MAGPIX readers.
Over the past decade and a half, life science researchers have relied on Luminex bead-based immunoassays to gain more information from less sample in less time. Bio-Rad’s years of experience with xMAP technology have provided the company with in-depth knowledge and an understanding of the needs of multiplex users, including their desire for automation and a simplified user experience.
The Bio-Plex Manager MP Software Upgrade brings the benefits of Bio-Plex Manager MP software, including automated instrument management, to all Luminex-based MAGPIX readers.
Bio-Plex Manager MP software offers an automated instrument management function, a unique feature that guides routine maintenance of the instrument based on its current status and performance. This automated feature ensures high quality data and optimal performance by:
- Automatically loading start-of-day maintenance routines based on instrument status
- Monitoring performance during data acquisition, alerting the user of performance issues, and resolving those issues
- Recommending simple stepwise troubleshooting
All of these benefits are now available for all Luminex-based MAGPIX readers through the Bio-Plex Manager MP Software Upgrade.
For more information on Bio-Rad’s Bio-Plex product portfolio, please visit www.bio-rad.com/bioplex.
The discovery of the double-helix structure of DNA 60 years ago led to a revolution in biological science, opening the floodgates for myriad subsequent discoveries and spawning new fields of research. Bio-Rad has been there from the beginning, helping scientists, educators, and clinicians advance basic research and improve healthcare. As we celebrate Bio-Rad’s diamond anniversary, we reflect on the major events in the evolution of life science research, from biochemistry to molecular biology and beyond, and the emergence of modern biotechnology.
High purity protein is a common requirement for biochemical and structural studies. A common approach is to recombinantly express an affinity-tagged version of the protein of interest. This is, however, not always a viable option. Some proteins are unstable or inactive once tagged or require posttranslational modifications that do not permit recombinant expression. In these cases, researchers often settle for lower purity protein rather than exhaustively explore purification options, since the purification optimization process can be time and labor intensive when no particular column resins or buffer conditions are dictated by an affinity tag.
Bio-Rad Laboratories has recently released a study demonstrating how to purify untagged protein to high homogeneity without undergoing laborious manual troubleshooting steps. Bio-Rad’s ChromLab software can be programmed to execute several runs sequentially thereby automating and accelerating this tedious process.
To learn how to purify untagged protein with ease read Protein Purification Workflow Development Using Bio-Rad’s NGC™ Chromatography System.
Droplet Digital PCR (ddPCR™) enables accurate, precise, and sensitive quantification of specific nucleic acid sequences. In addition to the standard detection of two targets using two different fluorophores, it is possible to increase the number of targets detected by varying parameters that affect PCR efficiency and end-point fluorescence. In this case, we describe a method to multiplex assays by varying the concentrations of primers and probes or the type of fluorophores used. This allows users to expand the number of simultaneously detected targets up to four. Increasing the number of potential targets per test is a significant improvement for ddPCR, dramatically augmenting the information output of each sample.