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Archive for the ‘cool tools’ Category

A Simple Way to Label Your Own Antibodies

 :: Posted by American Biotechnologist on 03-13-2014

Bio-Rad Laboratories announced the launch of its ReadiLink antibody labeling kits, one of the market’s simplest antibody conjugation solution for labeling microscale amounts (50–100 µg) of antibody. These kits are ideal for researchers interested in labeling their own antibodies for flow cytometry and cell sorting applications.

Using the ReadiLink antibody labeling kits, researchers can label their antibodies in two easy steps. The protocol takes only 70 minutes, and the labels are as bright and photostable as traditional dyes. Bio-Rad offers 10 different fluorophores whose excitation/emission wavelengths range from UV to infrared.

ReadiLink antibody labeling kits permit fluorophore conjugation of antibodies in two simple steps.

“The labeling kits will benefit a wide range of researchers,” said Mary Ferrero, Bio-Rad Product Manager in the Gene Expression Division, Life Sciences Group. “ReadiLink antibody labeling kits are ideal for researchers who are using a rare antibody, are interested in an antibody that is not commercially available with the appropriate fluorophore, or who want to label an antibody with a fluorophore that will fit into their multicolor flow cytometric experiment.”

Bio-Rad also offers additional reagents and consumables for each step of flow cytometry experiments, such as the ReadiDrop™ cell viability assays and primary antibodies.

For more information about Bio-Rad’s antibody labeling kits, please visit www.bio-rad.com/antibodylabeling.

How Google Glass Will Change Science

 :: Posted by American Biotechnologist on 01-23-2014

Google Glass is still in its infancy, however, the potential breakthroughs that it can offer in the fields of medicine and science are astounding.

Surgeons at the Ohio State University Medical Center are already using the device as a training and consulting tool while in the midst of surgery. Physician wearing Google Glass are able to transmit a live video feed to colleagues and medical students anywhere in the world. This is a true game changer in education as it gives students valuable exposure to live surgery in real-time from a surgeon’s point of view.

Aside from it’s communicational value, Google Glass has the potential to actually be used as an integral part of surgical practice. Physicians hope to be able to call up medical images or other important patient data during the course of surgery.

Now imagine combining Google Glass with procedures that incorporated fluorescently labeled dyes capable of differentiating cancerous tumors from benign growths or nerve from muscle. Surgeons such as Quyen Nguyen are already currently shining light onto labeled tumors and nerves to accomplish this goal (see Lighting up the operating room). With Google Glass, this procedure would become so much easier.

While medical applications sound very cool, what will be of most interest to our readers are the potential laboratory bench applications. How about using Google Glass for fluorescent imaging at the bench? Or calling up protocols while setting up an experiment? The possibilities are endless.

What applications can you imagine for Google Glass in your daily research?

Want To Become An Official American Biotechnologists Correspondent?

 :: Posted by American Biotechnologist on 12-02-2013

Happy December!

We are seeking Official Correspondents from Professors, PIs, Graduate Students, Technicians and Science Educators in university and college labs, biotech start-ups and other institutions.

How to get involved?

  1. Subscribe to American Biotechnologist http://www.americanbiotechnologist.com/blog/ to receive all our posts.
  2. Leave a comment on our new American Biotechnologists page or email us at info (at) americanbiotechnologist.com to indicate your interest in contributing to the blog.
  3. What to contribute? Well, we are open, as long your videos, podcasts, favorite links, images, selfies, infographics, posters, or text cover the field of biotechnology. If you are using Bio-Rad products we would be especially interested in hearing from you! Present your news, events, career aspirations, resumes, reflections, aspirations, gripes, pet peeves, research, unpublished musings, how to’s, how not to’s, fiction, art, or whatever. We are open as to length – short blog posts are fine – and how often you contribute- it’s up to you.
  4. As one of our Official American Biotechnologists Correspondents we will can put your picture and bio on the blog, if you want.

While we are still working out the details there will be special opportunities to our Official Correspondents. Perhaps field testing new Bio-Rad technologies, special offers, samples, etc. – cool stuff we assure you….

So as the Holiday season descends upon us and perhaps you have a bit of time, take a stab at contributing to an important community of interest – The Biotechnologists of America!

Regards,

The American Biotechnologist Blog

Lab on a chip….on a cell phone!

 :: Posted by American Biotechnologist on 11-18-2013

In developing nations, rural areas, and even one’s own home, limited access to expensive equipment and trained medical professionals can impede the diagnosis and treatment of disease. Many qualitative tests that provide a simple “yes” or “no” answer (like an at-home pregnancy test) have been optimized for use in these resource-limited settings. But few quantitative tests—those able to measure the precise concentration of biomolecules, not just their presence or absence—can be done outside of a laboratory or clinical setting. By leveraging their discovery of the robustness of “digital,” or single-molecule quantitative assays, researchers at the California Institute of Technology (Caltech) have demonstrated a method for using a lab-on-a-chip device and a cell phone to determine a concentration of molecules, such as HIV RNA molecules, in a sample. This digital approach can consistently provide accurate quantitative information despite changes in timing, temperature, and lighting conditions, a capability not previously possible using traditional measurements.

Read more…

Making high-end microscopy affordable for the masses

 :: Posted by American Biotechnologist on 07-29-2013

Engineers at the California Institute of Technology (Caltech) have devised a method to convert a relatively inexpensive conventional microscope into a billion-pixel imaging system that significantly outperforms the best available standard microscope. Such a system could greatly improve the efficiency of digital pathology, in which specialists need to review large numbers of tissue samples. By making it possible to produce robust microscopes at low cost, the approach also has the potential to bring high-performance microscopy capabilities to medical clinics in developing countries. – See more at: http://www.caltech.edu/content/pushing-microscopy-beyond-standard-limits