Posts Tagged ‘Surface Plasmon Resonance’

Using Bio-Rad’s ProteOn XPR36 for Antibody Characterization and Development

 :: Posted by American Biotechnologist on 03-25-2010

The Bio-Rad ProteOn XPR36 is a surface plasmon resonance (SPR) system capable of analyzing 36 protein-protein interactions in one experiment. Up to 6 antibodies may be simultaneously immobilized in parallel channels and assayed with panels of up to 6 antigens.

The Antibody Characterization and Development Using the Bio-Rad ProteOn technical note describes how the ProteOn can be used for:

  • Hybridoma screening and ranking
  • Epitope mapping
  • Kinetic analysis of antibody-antigen specificity
  • Determination of cross-reactivity of antibodies used in multiplex assays
  • For a great primer on Bio-Rad’s ProteOn XPR36 check out this brief video tour