Posts Tagged ‘american biotechnologist’

Nature wins hands down when it comes to creating cheap DNA sequencing technology

 :: Posted by American Biotechnologist on 03-26-2012

As hard as we try, we just can’t beat nature at creating efficient and amazing technologies.

In a fascinating feat of science, University of Washington scientists have created a tiny, nanoscale DNA sequencer that is capable of sequencing DNA strands of 42 to 53 nucleotides at a reasonable rate and at a fraction of the cost of conventional sequencing.

The biological sequencer consists of a mycobacterium nanopore placed in a membrane and surrounded by potassium-chloride solution. The DNA strand is pulled through the nanopore by phi29 DNA polymerase, an enzyme associated with replication of the phi29 virus. As the nucleotides pass through the nanopore, a small voltage is applied to create an ion current flowing through the nanopore whose electrical signature changes depending on the type of nucleotide traveling through the nanopore.

The results can be read online in this week’s edition of Nature Biotechnology.

Where have all the young profs gone?

 :: Posted by American Biotechnologist on 02-16-2012

In a very interesting study on Principle Investigator demographics, Dr. Sally Rockey, Director of Extramural Research at the NIH, found that over the last 32 years the average age distribution of NIH principle investigators has increased significantly. Watch the video below to see a shocking visual representation of the data. As a note to our PI population, although hearing loss is common in the elderly, your inability to hear what’s being said in this video is not a sign of aging. The video does not have any sound!

See Rock Talk for the full story.

What is the connection between cartoons, mitochondrial tweezers and Elizabeth Taylor’s eyes?

 :: Posted by American Biotechnologist on 12-29-2011

What is the connection between science cartoons, mitochondrial tweezers and Elizabeth Taylor’s eyes? If you guessed that they are all on the list of top 10 American Biotechonologist posts for 2011 you’d be right!

Our goal is to have fun, learn something and spread some scientific love. We hope that we have fulfilled our mission in 2011 and we look forward to a great 2012. Below is our top 10 of 2011. Feel free to comment and to let us know what you’d like to see more of (or less of) in the coming year.

Best wishes for a happy and healthy 2012!

  1. Awesome cartoon! How scientists see each other
  2. Mitochondrial tweezers revolutionize genetic research
  3. How realistic is your perception of science?
  4. Elizabeth Taylor’s eyes reveal the mysteries of the human genome
  5. PCR Assay for Chromatin Accessibility
  6. qPCR delta-delta Ct method simplified
  7. irrelevant RNA found to be crucial for protein selection
  8. Transfecting primary cells with high efficiency
  9. Scientists uncover new DNA role in modifying gene function
  10. Novel technique reveals both gene number and protein expression simultaneously

Merry Christmas from American Biotechnologist

 :: Posted by American Biotechnologist on 12-25-2011