Following up on yesterday’s post “New Layer of Genetic Information Discovered,” here is a talk by Professor Jonathan Weissman on applications of the ribosome profiling approach. The talk covers:
- Development of ribosome profiling protocols for a wide variety of eukaryotic and prokaryotic organisms.
- Uses of ribosome profiling to globally monitor when chaperones, targeting factors or processing enzymes engage nascent chains.
- Deciphering the driving force and biological consequences underlying the choice of synonymous codons.