New strategies for decoding genomes

Following up on yesterday’s post “New Layer of Genetic Information Discovered,” here is a talk by Professor Jonathan Weissman on applications of the ribosome profiling approach. The talk covers:

  1. Development of ribosome profiling protocols for a wide variety of eukaryotic and prokaryotic organisms.
  2. Uses of ribosome profiling to globally monitor when chaperones, targeting factors or processing enzymes engage nascent chains.
  3. Deciphering the driving force and biological consequences underlying the choice of synonymous codons.

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