In a joint study, scientists from the California and Florida campuses of The Scripps Research Institute have shown that changes in a protein’s structure can change its signaling function and they have pinpointed the precise regions where those changes take place.
The new findings could help provide a much clearer picture of potential drugs that would be both effective and highly specific in their biological actions.
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In another study published in Nature this past summer, Harvard scientists demonstrated that the shape of a protein plays a critical role in its function. See the video below for details.