James Watson describes how he discovered DNA
Although 2013 was a terrible year for research funding, there is some indication that American scientists might see in increase in their spending budget this coming year. According to an Associated Press article posted in OA online 6 days ago, the government has earmarked $29.9 billion out of its $1.1 trillion 2014 spending budget for the National Institute of Health (NIH). This represents a $1 billion dollar increase above 2013 funding levels and will provide a much needed boost to the drastic drop in research funding caused by the sequester.
Yet despite its positive tone, others are cautioning that the $1 billion increase may not be enough. According to Sen. Bod Casey of Pennsylvania, the proposes 2014 budget, increase and all, still falls way short of the NIH’s 2009 funding levels. Furthermore, according to the Huffington Post, the 2014 budget is $714 million less than pre-sequestration NIH funding and smaller than all of President George W. Bush’s NIH budgets with the exception of his first year in office.
The publication Nature offered a further glimpse into how the so-called funding-boost may really be less rosy than it appears for biomedical research. According to Nature, the funding increase will provide physical science research with small increases over 2012 levels. On the other hand, biomedical research will actually experience a budget decline of approximately $800 million below 2012 funding levels. According to the Whit House Office of Management and Budget, the NIH will receive $29,926 million in 2014 compared to $30,702 in 2012 and the CDC will receive $5,807 million in 2014 compared to $5,656 in 2012. Taking into account the impact of inflation, these numbers seem particularly dismal.
What lesson needs to be learned from this story? The next time you hear that the US is on the road to recovery, be sure to check your blind spots before changing lanes. You may be surprised at the dangers that are lurking behind you.
Like the strings on a violin or the pipes of an organ, the proteins in the human body vibrate in different patterns, scientists have long suspected.
Now, a new study provides what researchers say is the first conclusive evidence that this is true.
Using a technique they developed based on terahertz near-field microscopy, scientists from the University at Buffalo and Hauptman-Woodward Medical Research Institute (HWI) have for the first time observed in detail the vibrations of lysozyme, an antibacterial protein found in many animals.
The team found that the vibrations, which were previously thought to dissipate quickly, actually persist in molecules like the “ringing of a bell,” said UB physics professor Andrea Markelz, PhD, wh0 led the study.
These tiny motions enable proteins to change shape quickly so they can readily bind to other proteins, a process that is necessary for the body to perform critical biological functions like absorbing oxygen, repairing cells and replicating DNA, Markelz said.
The research opens the door to a whole new way of studying the basic cellular processes that enable life.
So you’ve reached the top of the academic ladder and decided to do a PhD. You’ve performed at the top of your class for as long as you can remember. School has been a breeze. You are ready for the challenge.
So why are you finding the PhD program so darn difficult?
According to James Hayton from The Three Month Thesis, you are likely finding the PhD difficult because you are looking at it the wrong way.