Have you ever thought about what genomic DNA and MP3 headphones have in common? Dr. Erez Leiberman Aiden has and it has netted him a prestigious $25,000 prize and a 5 year, $2.5M new investigator award. What does one thing have to do with the other? Read on to find out!
While researching our earlier post on 3-D genome mapping, I came across an interesting interview of Dr. Erez Lieberman Aiden, a PhD from Harvard and MIT and currently a fellow at the Harvard Society of Fellows and Visiting Faculty at Google.
In this interview, Dr. Aiden talks about his research into the 3 dimensional structure of genomic DNA. In 2009, Aiden and collegues published a technique called Hi-C which utilizes sequencing data to produce 3 dimensional images of genomic DNA and can be used to visualize how genomic DNA is folded in the nucleus of a cell. Considering the critical role that genomic DNA’s tertiary structure plays in genomic function, Hi-C structural maps are likely to become an important part of the functional genomic scientist’s repetoire.