A Robust Method for Detecting DNA Methylation

DNA methylation is one of the most studied epigenetic modifications. DNA methylation plays an important role in a number of physiological processes as well as common diseases such as cancer and neurodegenerative disorders. Recent data have shown a correlation of DNA methylation and disease status. However, there is an unmet need for a sensitive yet robust method to analyze DNA methylation in clinical samples.

In the bulletin “Droplet Digital PCR: Detection of DNA Methylation”, Bio-Rad Laboratories demonstrates teh unprecedented sensitivity, linearity and robustness of DNA methylation detection by ddPCR in a model system for an imprinted gene involved in neurological disorders.

Read “Droplet Digital PCR: Detection of DNA Methylation” for more information.

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