Engineers at the California Institute of Technology (Caltech) have devised a method to convert a relatively inexpensive conventional microscope into a billion-pixel imaging system that significantly outperforms the best available standard microscope. Such a system could greatly improve the efficiency of digital pathology, in which specialists need to review large numbers of tissue samples. By making it possible to produce robust microscopes at low cost, the approach also has the potential to bring high-performance microscopy capabilities to medical clinics in developing countries. – See more at: http://www.caltech.edu/content/pushing-microscopy-beyond-standard-limits
Archive for the ‘Interesting Studies’ Category
How a group of animals can abandon sex, yet produce more than 460 species over evolutionary time, became a little less mysterious this week with the publication of the complete genome of a bdelloid rotifer (Adineta vaga) in the journal Nature.
Mark Welch and his MBL colleague, Irina Arkhipova, are the U.S. leads on the international project to sequence the rotifer genome and analyze what it reveals.
Flot JF, et al (2013) Genomic evidence for ameiotic evolution in the bdelloid rotifer Adineta vaga. Nature 10.1038/nature12326
In a new paper published in the journal Nature, researchers present a previously unknown mechanism that controls whether a cell survives autophagy, a process that can be compared to the cell consuming parts of itself. The discovery means that it might now be possible to influence the process, which is involved in a wide variety of diseases.
Changes in the epigenome, including chemical modifications of DNA, can act as an extra layer of information in the genome, and are thought to play a role in learning and memory, as well as in age-related cognitive decline. The results of a new study by scientists at the Salk Institute for Biological Studies show that the landscape of DNA methylation, a particular type of epigenomic modification, is highly dynamic in brain cells during the transition from birth to adulthood, helping to understand how information in the genomes of cells in the brain is controlled from fetal development to adulthood. The brain is much more complex than all other organs in the body and this discovery opens the door to a deeper understanding of how the intricate patterns of connectivity in the brain are formed.